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collagen 1 type a1  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc collagen 1 type a1
    Collagen 1 Type A1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 89 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/collagen+1+type+a1/COL1A1+Rabbit+mAb/10__1161_slash_circheartfailure__125__013806-177-8-12
    Average 95 stars, based on 89 article reviews
    collagen 1 type a1 - by Bioz Stars, 2026-10
    95/100 stars

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    Fig. 5 RNA-seq and Target-TF Prediction Suggest sEV inhibits fibrosis via STAT3. A Volcano plot of DEGs between the TGF-β group and the TGF-β + sEV group. B GSEA of GO terms related to cellular components. C Heatmap showing downregulation of Col1 A1 and Acta2 expression by sEV in TGF-β-stimulated hSGFs. D Prediction of transcription factors (TFs) regulating Col1A1 and Acta2 using KnockTF, ENCODE, GTRD, and ChIP-Atlas databases, identifying SP1, GATA3, and STAT3 as potential candidates. E Heatmap showing that sEV downregulates STAT3 rather than SP1 and GATA3 expression in TGF-β-stimulated hSGFs

    Journal: Journal of translational medicine

    Article Title: Saliva-derived extracellular vesicles: a promising therapeutic approach for salivary gland fibrosis.

    doi: 10.1186/s12967-025-06620-1

    Figure Lengend Snippet: Fig. 5 RNA-seq and Target-TF Prediction Suggest sEV inhibits fibrosis via STAT3. A Volcano plot of DEGs between the TGF-β group and the TGF-β + sEV group. B GSEA of GO terms related to cellular components. C Heatmap showing downregulation of Col1 A1 and Acta2 expression by sEV in TGF-β-stimulated hSGFs. D Prediction of transcription factors (TFs) regulating Col1A1 and Acta2 using KnockTF, ENCODE, GTRD, and ChIP-Atlas databases, identifying SP1, GATA3, and STAT3 as potential candidates. E Heatmap showing that sEV downregulates STAT3 rather than SP1 and GATA3 expression in TGF-β-stimulated hSGFs

    Article Snippet: The following primary antibodies were used: CD9 (Abcam, ab236630, 1:1000), Alix (Abcam, ab275377, 1:1000), TSG101 (Abcam, ab125011, 1:1000), Calnexin (Cell signaling technology, #2433, 1:1000), STAT3 (Proteintech, 10253-2-AP, 1:1000), p-STAT3 (HUABIO ET160340, 1:1000), αSMA (Proteintech, 14395-1-AP, 1:1000), Col1 A1 (Proteintech, 14695-1-AP, 1:1000), and GAPDH (Bioswamp, PAB33921, 1:5000).

    Techniques: RNA Sequencing, Expressing